In orthodontic treatment, the biological response of the tooth, periodontal ligament, and bone complex to orthodontic force is crucial in influencing treatment outcomes. The challenge lies in accurately measuring, estimating, and predicting these forces during clinical procedures. This review aims to fill the gap in the literature by systematically summarizing existing research on orthodontic force simulation, examining common loading techniques and technologies, and discussing the potential for refining the orthodontic force simulation process. The literature was comprehensively reviewed, with an emphasis on the exploration of the biological mechanism of tooth movement. Studies were categorized based on force-loading techniques for both fixed and invisible orthodontic appliances. Finite element (FE) analysis stands out as the predominant technique for orthodontic force simulation, with a significant focus on fixed orthodontics but limited emphasis on invisible orthodontics. Current orthodontic force simulations tend to be fragmented, often considering only the instantaneous response to applied forces. There exists an urgent demand for a sophisticated analytical simulation model. Such a model, possibly leveraging advanced technologies like deep learning, holds the promise of forecasting orthodontic treatment outcomes with heightened precision and efficiency.
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