Weighting methods are a common tool to de-bias estimates of causal effects. And though there are an increasing number of seemingly disparate methods, many of them can be folded into one unifying regime: causal optimal transport. This new method directly targets distributional balance by minimizing optimal transport distances between treatment and control groups or, more generally, between a source and target population. Our approach is model-free but can also incorporate moments or any other important functions of covariates that the researcher desires to balance. We find that the causal optimal transport outperforms competitor methods when both the propensity score and outcome models are misspecified, indicating it is a robust alternative to common weighting methods. Finally, we demonstrate the utility of our method in an external control study examining the effect of misoprostol versus oxytocin for treatment of post-partum hemorrhage.
翻译:加权方法是降低因果关系估计的常见工具。 虽然似乎有越来越多的不同方法,但其中许多方法可以合并为一个统一机制:因果最佳运输。这一新方法通过最大限度地减少治疗和控制组之间或更一般地说,源与目标人群之间的最佳运输距离,直接针对分配平衡。我们的方法是没有模型的,但也可以包括研究者想要平衡的因果混合过程或任何其他重要功能。我们发现,当偏向性分和结果模型被错误地描述时,因果最佳运输优于竞争方法,表明它是常见加权方法的有力替代方法。最后,我们在一项外部控制研究中展示了我们的方法对治疗产后出血的厌食和催产素的效果的实用性。