The virtualization and softwarization of 5G and NextG are critical enablers of the shift to flexibility, but they also present a potential attack surface for threats. However, current security research in communication systems focuses on specific aspects of security challenges and lacks a holistic perspective. To address this challenge, a novel systematic fuzzing approach is proposed to reveal, detect, and predict vulnerabilities with and without prior knowledge assumptions from attackers. It also serves as a digital twin platform for system testing and defense simulation pipeline. Three fuzzing strategies are proposed: Listen-and-Learn (LAL), Synchronize-and-Learn (SyAL), and Source-and-Learn (SoAL). The LAL strategy is a black-box fuzzing strategy used to discover vulnerabilities without prior protocol knowledge, while the SyAL strategy, also a black-box fuzzing method, targets vulnerabilities more accurately with attacker-accessible user information and a novel probability-based fuzzing approach. The white-box fuzzing strategy, SoAL, is then employed to identify and explain vulnerabilities through fuzzing of significant bits. Using the srsRAN 5G platform, the LAL strategy identifies 129 RRC connection vulnerabilities with an average detection duration of 0.072s. Leveraging the probability-based fuzzing algorithm, the SyAL strategy outperforms existing models in precision and recall, using significantly fewer fuzzing cases. SoAL detects three man-in-the-middle vulnerabilities stemming from 5G protocol vulnerabilities. The proposed solution is scalable to other open-source and commercial 5G platforms and protocols beyond RRC. Extensive experimental results demonstrate that the proposed solution is an efficient and efficient approach to validate 5G security; meanwhile, it serves as real-time vulnerability detection and proactive defense.
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