Many studies employ the analysis of time-to-event data that incorporates competing risks and right censoring. Most methods and software packages are geared towards analyzing data that comes from a continuous failure time distribution. However, failure-time data may sometimes be discrete either because time is inherently discrete or due to imprecise measurement. This paper introduces a novel estimation procedure for discrete-time survival analysis with competing events. The proposed approach offers two key advantages over existing procedures: first, it accelerates the estimation process; second, it allows for straightforward integration and application of widely used regularized regression and screening methods. We illustrate the benefits of our proposed approach by conducting a comprehensive simulation study. Additionally, we showcase the utility of our procedure by estimating a survival model for the length of stay of patients hospitalized in the intensive care unit, considering three competing events: discharge to home, transfer to another medical facility, and in-hospital death.
翻译:许多研究采用对时间对活动数据的分析,将相互竞争的风险和正确的审查纳入其中。大多数方法和软件包都着眼于分析来自持续失败时间分布的数据。然而,由于时间本身是独立的,或由于测量不精确,故障时间数据有时可能互不相关。本文对与竞争事件分开的求生分析采用了新的估计程序。拟议方法比现有程序提供了两个主要优势:首先,它加快了估算过程;第二,它允许直接整合和应用广泛使用的常规回归和筛选方法。我们通过进行全面模拟研究来说明我们拟议方法的效益。此外,我们通过估计在强化护理单位住院病人的住院时间长短的存活模式来展示我们的程序的效用,考虑到三个相互竞争的事件:出院、转移到另一个医疗设施以及住院死亡。</s>