基于纳米结构阵列的SERS效应对痕量多氯联苯的快速检测

项目名称： 基于纳米结构阵列的SERS效应对痕量多氯联苯的快速检测

项目编号： No.11274312

项目类型： 面上项目

立项/批准年度： 2013

项目学科： 数理科学和化学

项目作者： 孟国文

作者单位： 中国科学院合肥物质科学研究院

项目金额： 81万元

中文摘要： 多氯联苯(PCBs)危及人类健康，且其危害具有累积性，痕量PCBs就会造成极大危害。目前实验室采用色/质谱等方法检测PCBs，需要萃取、浓缩、净化等繁琐的过程；虽然能实现痕量检测，但却无法实现快速检测。而痕量PCBs的快速检测至关重要，对突发、应急事件的预警与跟踪具有极其重要的意义。贵金属纳米结构的表面等离子体共振会引起局域场增强；当待检物吸附在其表面时，其拉曼信号强度会大幅度提高，产生表面增强拉曼散射(SERS)效应。由于拉曼光谱测量快，所以利用纳米结构SERS效应有望实现对痕量PCBs的快速检测。本项目将研究构筑SERS活性高、信号均匀、稳定、可重复的纳米结构的方法；筛选对PCBs特异性选择吸附的物质，并将其修饰在纳米结构表面，以便有效捕捉痕量PCBs；研究纳米结构对PCBs拉曼信号增强的规律与机理；为基于纳米结构SERS效应快速检测痕量PCBs提供科学依据，对环境健康具有重要意义。

中文关键词： 纳米结构阵列；表面增强拉曼散射；高灵敏度；快速检测；多氯联苯

英文摘要： Polychlorinated biphenyls (PCBs) can cause harmful biological effects, and they can bio-accumulate in fatty tissues through food chains, so even small exposures eventually reach dangerous levels. Therefore, urgent actions have been called to dispose PCBs globally. Traditional laboratory techniques for the detection of trace PCBs include high-resolution capillary gas chromatographic columns with an electron capture detector, immunoassays, and high-resolution mass spectrometry. But these conventional methods are generally costly and time-consuming as tedious and complex pre-treatments have to be carried out. Rapid and sensitive detection of PCBs is therefore exigent and extremely important. Surface-enhanced Raman scattering (SERS) is one of the most powerful probing tools for rapid trace detection of organic chemicals because it enables ultrasensitive, low-cost and real-time detection. The nanometer-scale gaps, sharp tips and edges are believed to have highly concentrated electromagnetic fields associated with strong localized surface plasmonic resonance so that "hot spots" occur at these positions. For effective SERS substrates, it is generally required to have enough hot spots to ensure high SERS sensitivity, the uniformity of the substrate to ensure good reproducibility for SERS measurements, and the ability to

英文关键词： Nanostructures；SERS；High sensitivity；Rapid detection；PCBs