Insertion, deletion, and substitution (IDS) error-correcting codes have garnered increased attention with recent advancements in DNA storage technology. However, a universal method for designing IDS-correcting codes across varying channel settings remains underexplored. We present an autoencoder-based method, THEA-code, aimed at efficiently generating IDS-correcting codes for complex IDS channels. In the work, a Gumbel-Softmax discretization constraint is proposed to discretize the features of the autoencoder, and a simulated differentiable IDS channel is developed as a differentiable alternative for IDS operations. These innovations facilitate the successful convergence of the autoencoder, resulting in channel-customized IDS-correcting codes with commendable performance across complex IDS channels.
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