Artificial Data Point Generation in Clustered Latent Space for Small Medical Datasets

One of the growing trends in machine learning is the use of data generation techniques, since the performance of machine learning models is dependent on the quantity of the training dataset. However, in many medical applications, collecting large datasets is challenging due to resource constraints, which leads to overfitting and poor generalization. This paper introduces a novel method, Artificial Data Point Generation in Clustered Latent Space (AGCL), designed to enhance classification performance on small medical datasets through synthetic data generation. The AGCL framework involves feature extraction, K-means clustering, cluster evaluation based on a class separation metric, and the generation of synthetic data points from clusters with distinct class representations. This method was applied to Parkinson's disease screening, utilizing facial expression data, and evaluated across multiple machine learning classifiers. Experimental results demonstrate that AGCL significantly improves classification accuracy compared to baseline, GN and kNNMTD. AGCL achieved the highest overall test accuracy of 83.33% and cross-validation accuracy of 90.90% in majority voting over different emotions, confirming its effectiveness in augmenting small datasets.