Modelling, analysing and inferring triggering mechanisms in population reproduction is fundamental in many biological applications. It is also an active and growing research domain in mathematical biology. In this chapter, we review the main results developed over the last decade for the estimation of the division rate in growing and dividing populations in a steady environment. These methods combine tools borrowed from PDE's and stochastic processes, with a certain view that emerges from mathematical statistics. A focus on the application to the bacterial cell division cycle provides a concrete presentation, and may help the reader to identify major new challenges in the field.
翻译:人口生殖的建模、分析和推断触发机制在许多生物应用中具有根本意义,也是数学生物学中一个活跃和不断增长的研究领域,在本章中,我们审查了过去十年来为估计稳定环境中人口增长和分裂的分化率而取得的主要结果,这些方法结合了从PDE和随机过程借用的工具,从数学统计中得出某种观点,侧重于对细菌细胞分解周期的应用,提供了具体的介绍,并可能帮助读者确定该领域的主要新挑战。