This paper introduces a framework for an indoor autonomous mobility system that can perform patient transfers and materials handling. Unlike traditional systems that rely on onboard perception sensors, the proposed approach leverages a global perception and localization (PL) through Infrastructure Sensor Nodes (ISNs) and cloud computing technology. Using the global PL, an integrated Model Predictive Control (MPC)-based local planning and tracking controller augmented with Artificial Potential Field (APF) is developed, enabling reliable and efficient motion planning and obstacle avoidance ability while tracking predefined reference motions. Simulation results demonstrate the effectiveness of the proposed MPC controller in smoothly navigating around both static and dynamic obstacles. The proposed system has the potential to extend to intelligent connected autonomous vehicles, such as electric or cargo transport vehicles with four-wheel independent drive/steering (4WID-4WIS) configurations.
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