Deep Neural Decision Forest: A Novel Approach for Predicting Recovery or Decease of COVID-19 Patients with Clinical and RT-PCR

COVID-19 continues to be considered an endemic disease in spite of the World Health Organization's declaration that the pandemic is over. This pandemic has disrupted people's lives in unprecedented ways and caused widespread morbidity and mortality. As a result, it is important for emergency physicians to identify patients with a higher mortality risk in order to prioritize hospital equipment, especially in areas with limited medical services. The collected data from patients is beneficial to predict the outcome of COVID-19 cases, although there is a question about which data makes the most accurate predictions. Therefore, this study aims to accomplish two main objectives. First, we want to examine whether deep learning algorithms can predict a patient's morality. Second, we investigated the impact of Clinical and RT-PCR on prediction to determine which one is more reliable. We defined four stages with different feature sets and used interpretable deep learning methods to build appropriate model. Based on results, the deep neural decision forest performed the best across all stages and proved its capability to predict the recovery and death of patients. Additionally, results indicate that Clinical alone (without the use of RT-PCR) is the most effective method of diagnosis, with an accuracy of 80%. It is important to document and understand experiences from the COVID-19 pandemic in order to aid future medical efforts. This study can provide guidance for medical professionals in the event of a crisis or outbreak similar to COVID-19.