In the field of medical image analysis, there is a substantial need for high-resolution (HR) images to improve diagnostic accuracy. However, it is a challenging task to obtain HR medical images, as it requires advanced instruments and significant time. Deep learning-based super-resolution methods can help to improve the resolution and perceptual quality of low-resolution (LR) medical images. Recently, Generative Adversarial Network (GAN) based methods have shown remarkable performance among deep learning-based super-resolution methods. Real-Enhanced Super-Resolution Generative Adversarial Network (Real-ESRGAN) is a practical model for recovering HR images from real-world LR images. In our proposed approach, we use transfer learning technique and fine-tune the pre-trained Real-ESRGAN model using medical image datasets. This technique helps in improving the performance of the model. We employ the high-order degradation model of the Real-ESRGAN which better simulates real-world image degradations. This adaptation allows for generating more realistic degraded medical images, resulting in improved performance. The focus of this paper is on enhancing the resolution and perceptual quality of chest X-ray and retinal images. We use the Tuberculosis chest X-ray (Shenzhen) dataset and the STARE dataset of retinal images for fine-tuning the model. The proposed model achieves superior perceptual quality compared to the Real-ESRGAN model, effectively preserving fine details and generating images with more realistic textures.
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