QPanda3 is a high-performance quantum programming framework that enhances quantum computing efficiency through optimized circuit compilation, an advanced instruction stream format (OriginBIS), and hardware-aware execution strategies. These engineering optimizations significantly improve both processing speed and system performance, addressing key challenges in the NISQ era. A core innovation, OriginBIS, accelerates encoding speeds by up to 86.9x compared to OpenQASM 2.0, while decoding is 35.6x faster, leading to more efficient data handling, reduced memory overhead, and improved communication efficiency. This directly enhances the execution of quantum circuits, making large-scale quantum simulations more feasible. Comprehensive benchmarking demonstrates QPanda3's superior performance: quantum circuit construction is 20.7x faster, execution speeds improve by 3.4x, and transpilation efficiency increases by 14.97x over Qiskit. Notably, in compiling a 118-qubit W-state circuit on a 2D-grid topology, QPanda3 achieves an unprecedented 869.9x speedup, underscoring its ability to handle complex quantum workloads at scale. By combining high-speed quantum processing with a modular and extensible software architecture, QPanda3 provides a practical bridge between today's NISQ devices and future fault-tolerant quantum computing. It facilitates real-world applications in financial modeling, materials science, and combinatorial optimization, while its robust and scalable design supports industrial adoption and cloud-based deployment.
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