Adversarial examples have raised widespread attention in security-critical applications because of their transferability across different models. Although many methods have been proposed to boost adversarial transferability, a gap still exists in the practical demand. In this paper, we argue that the model-specific discriminative regions are a key factor to cause the over-fitting to the source model, and thus reduce the transferability to the target model. For that, a patch-wise mask is utilized to prune the model-specific regions when calculating adversarial perturbations. To accurately localize these regions, we present a learnable approach to optimize the mask automatically. Specifically, we simulate the target models in our framework, and adjust the patch-wise mask according to the feedback of simulated models. To improve the efficiency, Differential Evolutionary (DE) algorithm is utilized to search for patch-wise masks for a specific image. During iterative attacks, the learned masks are applied to the image to drop out the patches related to model-specific regions, thus making the gradients more generic and improving the adversarial transferability. The proposed approach is a pre-processing method and can be integrated with existing gradient-based methods to further boost the transfer attack success rate. Extensive experiments on the ImageNet dataset demonstrate the effectiveness of our method. We incorporate the proposed approach with existing methods in the ensemble attacks and achieve an average success rate of 93.01% against seven advanced defense methods, which can effectively enhance the state-of-the-art transfer-based attack performance.
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