Skin cancer is a serious and potentially fatal disease caused by DNA damage. Early detection significantly increases survival rates, making accurate diagnosis crucial. In this groundbreaking study, we present a hybrid framework based on Deep Learning (DL) that achieves precise classification of benign and malignant skin lesions. Our approach begins with dataset preprocessing to enhance classification accuracy, followed by training two separate pre-trained DL models, InceptionV3 and DenseNet121. By fusing the results of each model using the weighted sum rule, our system achieves exceptional accuracy rates. Specifically, we achieve a 92.27% detection accuracy rate, 92.33% sensitivity, 92.22% specificity, 90.81% precision, and 91.57% F1-score, outperforming existing models and demonstrating the robustness and trustworthiness of our hybrid approach. Our study represents a significant advance in skin cancer diagnosis and provides a promising foundation for further research in the field. With the potential to save countless lives through earlier detection, our hybrid deep-learning approach is a game-changer in the fight against skin cancer.
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