Large language models (LLMs) have triggered tremendous success to empower daily life by generative information, and the personalization of LLMs could further contribute to their applications due to better alignment with human intents. Towards personalized generative services, a collaborative cloud-edge methodology sounds promising, as it facilitates the effective orchestration of heterogeneous distributed communication and computing resources. In this article, after discussing the pros and cons of several candidate cloud-edge collaboration techniques, we put forward NetGPT to capably deploy appropriate LLMs at the edge and the cloud in accordance with their computing capacity. In addition, edge LLMs could efficiently leverage location-based information for personalized prompt completion, thus benefiting the interaction with cloud LLMs. After deploying representative open-source LLMs (e.g., GPT-2-base and LLaMA model) at the edge and the cloud, we present the feasibility of NetGPT on the basis of low-rank adaptation-based light-weight fine-tuning. Subsequently, we highlight substantial essential changes required for a native artificial intelligence (AI) network architecture towards NetGPT, with special emphasis on deeper integration of communications and computing resources and careful calibration of logical AI workflow. Furthermore, we demonstrate several by-product benefits of NetGPT, given edge LLM's astonishing capability to predict trends and infer intents, which possibly leads to a unified solution for intelligent network management \& orchestration. In a nutshell, we argue that NetGPT is a promising native-AI network architecture beyond provisioning personalized generative services.
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