项目名称: 维吾尔药刺糖对消化道作用的研究
项目编号: No.31460677
项目类型: 地区科学基金项目
立项/批准年度: 2015
项目学科: 农业科学
项目作者: 米克热木·沙衣布扎提
作者单位: 新疆农业大学
项目金额: 50万元
中文摘要: 维吾尔医学历史悠久,具有鲜明的地域特色。刺糖为豆科骆驼刺属植物骆驼刺的分泌糖粒,是传统的维吾尔民间药物。在新疆来源丰富,价格低廉,维吾尔医将之与其它药材配伍,用于治疗痢疾、腹泻、胃脘胀痛、血尿、糖尿病及小孩便秘等疾病。是用于滋补强壮和平衡体液、润肠通便、调节内分泌的常见验方,至今普遍使用。目前,其研究仅为成分分析阶段,药效方面的研究鲜见报道,实验动物体内作用机制的研究未见报道。本研究就刺糖对实验动物在体和离体小肠平滑肌收缩功能研究的基础上,从受体水平和消化液成分改变来研究刺糖调节胃肠平滑肌功能的机制。进一步深入了解刺糖的药效学特点,尤其是防治幼畜胃肠道疾病中推广应用提供理论依据。为进一步开发新疆兽用维吾尔药材奠定基础。
中文关键词: 刺糖;小肠平滑肌;受体;消化液
英文摘要: Uygur medicine has a long history and distinct regional features. Alhagi sugar for Leguminosae plants of the alhagi genus alhagi secretion sugar granule,is the traditional uygur folk medicine.The plants rich in resourse of Xinjiang,low price,Uygur medicine compatibility of other medicinal materials , Used in treating of dysentery ,diarrhea,epigastric pain,hematuria,diabetes and child constipation ect disease.Is used for nourishing and strong and fluid balance,relaxing bowel,Regulating endocrine common prescription, used to commonly so far.At present,The research is only component analysis stage,the reports rare of pesticide effects side ,Laboratory animal body mechanism of action research has not reported.The purpose of this study is to alhagi sugar to animals in vivo and in vitro intestinal smooth muscle contraction function on the basis of the research,From the receptor level and digestive fluid composition change to study the algagi sugar regulating gastrointestinal smooth muscle function mecha-nism .Further understand algagi sugar pharmacodynamics characteristics,Especially in the prevention of pup gastrointestinal diseases to provide theoretical basis for popularization and application.Laid the foundation for the further development of xinjiang uygur medicine veterinary use.
英文关键词: Saccharu alhagi;Small Intestinal smooth;receptors;Digestive juice