Learning manipulation skills from human demonstration videos presents a promising yet challenging problem, primarily due to the significant embodiment gap between human body and robot manipulators. Existing methods rely on paired datasets or hand-crafted rewards, which limit scalability and generalization. We propose TrajSkill, a framework for Trajectory Conditioned Cross-embodiment Skill Transfer, enabling robots to acquire manipulation skills directly from human demonstration videos. Our key insight is to represent human motions as sparse optical flow trajectories, which serve as embodiment-agnostic motion cues by removing morphological variations while preserving essential dynamics. Conditioned on these trajectories together with visual and textual inputs, TrajSkill jointly synthesizes temporally consistent robot manipulation videos and translates them into executable actions, thereby achieving cross-embodiment skill transfer. Extensive experiments are conducted, and the results on simulation data (MetaWorld) show that TrajSkill reduces FVD by 39.6\% and KVD by 36.6\% compared with the state-of-the-art, and improves cross-embodiment success rate by up to 16.7\%. Real-robot experiments in kitchen manipulation tasks further validate the effectiveness of our approach, demonstrating practical human-to-robot skill transfer across embodiments.
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