The asymmetric simple exclusion process (ASEP) is a model of particle transport used in the study of biological processes such as mRNA translation. In 2014, Zhao and Krishnan introduced a new approach for analyzing the ASEP using probabilistic Boolean networks (PBN). In this paper, we revisit and further explore the PBN approach, with focus on computing steady state distributions. Explicit forms of the structure matrices of some common transitions are obtained. In addition, we derive a simplified method for computing the structure matrices of Boolean functions and a general method for writing the Boolean functions. These methods are also extended to multi-valued logic networks for application in multi-species exclusion processes.
翻译:不对称的简单排除过程(ASEP)是研究诸如 mRNA 翻译等生物过程时使用的一种粒子迁移模型。2014年,赵和克利须那采用了一种利用概率波林网络(PBN)分析ASEP的新方法。在本文件中,我们重新审视并进一步探索PBN方法,重点是计算稳定状态分布。获得了某些常见转变的结构矩阵的明确形式。此外,我们得出了一个计算布林函数结构矩阵的简化方法,以及写布林函数的一般方法。这些方法还推广到多价逻辑网络,用于多种排除进程。