High-Throughput Asset Pricing

We use empirical Bayes (EB) to mine for out-of-sample returns among 73,108 long-short strategies constructed from accounting ratios, past returns, and ticker symbols. EB predicts returns are concentrated in accounting and past return strategies, small stocks, and pre-2004 samples. The cross-section of out-of-sample return lines up closely with EB predictions. Data-mined portfolios have mean returns comparable with published portfolios, but the data-mined returns are arguably free of data mining bias. In contrast, controlling for multiple testing following Harvey, Liu, and Zhu (2016) misses the vast majority of returns. This "high-throughput asset pricing" provides an evidence-based solution for data mining bias.