Humankind's understanding of the world is fundamentally linked to our perception and cognition, with \emph{human languages} serving as one of the major carriers of \emph{world knowledge}. In this vein, \emph{Large Language Models} (LLMs) like ChatGPT epitomize the pre-training of extensive, sequence-based world knowledge into neural networks, facilitating the processing and manipulation of this knowledge in a parametric space. This article explores large models through the lens of ``knowledge''. We initially investigate the role of symbolic knowledge such as Knowledge Graphs (KGs) in enhancing LLMs, covering aspects like knowledge-augmented language model, structure-inducing pre-training, knowledgeable prompts, structured CoT, knowledge editing, semantic tools for LLM and knowledgeable AI agents. Subsequently, we examine how LLMs can amplify traditional symbolic knowledge bases, encompassing aspects like using LLM as KG builder and controller, structured knowledge pretraining, LLM-enhanced symbolic reasoning, and the amalgamation of perception with cognition. Considering the intricate nature of human knowledge, we advocate for the creation of \emph{Large Knowledge Models} (LKM), specifically engineered to manage diversified spectrum of knowledge structures. This ambitious undertaking could entail several key challenges, such as disentangling knowledge representation from language models, restructuring pre-training with structured knowledge, and building large commonsense models, among others. We finally propose a five-``A'' principle to distinguish the concept of LKM.
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