In an effort to provide regional decision support for the public healthcare, we design a data-driven compartment-based model of COVID-19 in Sweden. From national hospital statistics we derive parameter priors, and we develop linear filtering techniques to drive the simulations given data in the form of daily healthcare demands. We additionally propose a posterior marginal estimator which enables a refined resolution of the reproduction number estimate, and which also improves substantially on our confidence in the overall results thanks to a parametric bootstrap procedure. From our computational approach we obtain a Bayesian model of predictive value which provides important insight into the progression of the disease, including estimates of the effective reproduction number, the infection fatality rate, and the regional-level immunity. We successfully validate our posterior model against several different sources, including outputs from extensive screening programs. Since our required data in comparison is easy and non-sensitive to collect, we argue that our approach is particularly promising as a tool to support monitoring and decisions within public health.
翻译:为了努力为公众保健提供区域决策支持,我们设计了瑞典COVID-19的数据驱动区划模型。我们从国家医院统计数据中得出参数前科,我们开发线性过滤技术,驱动以日常保健需求形式提供的模拟数据。我们还提议了后边边估计器,使复制数字估计数得到更好的解析,并大大增强了我们对通过参数靴子捕捉程序取得的总体结果的信心。我们从计算方法中获得了巴耶斯预测值模型,该模型对疾病的演变提供了重要的洞察力,包括有效生殖数、感染死亡率和区域一级免疫率的估计。我们成功地根据多种不同来源,包括广泛的筛选方案的产出,验证了我们的后方模型。由于我们比较所需数据容易收集,而且不敏感,我们认为我们的方法特别有希望成为在公共卫生范围内支持监测和决策的工具。