From personalised medicine to targeted advertising, it is an inherent task to provide a sequence of decisions with historical covariates and outcome data. This requires understanding of both the dynamics and heterogeneity of treatment effects. In this paper, we are concerned with detecting abrupt changes in the treatment effects in terms of the conditional average treatment effect (CATE) in a sequential fashion. To be more specific, at each time point, we consider a nonparametric model to allow for maximal flexibility and robustness. Along the time, we allow for temporal dependence on historical covariates and noise functions. We provide a kernel-based change point estimator, which is shown to be consistent in terms of its detection delay, under an average run length control. Numerical results are provided to support our theoretical findings.
翻译:从个性医学到有针对性的广告,提供一系列具有历史共变和结果数据的决定是一项固有任务,这要求了解治疗效果的动态和异质性。在本文中,我们关注以顺序方式检测有条件平均治疗效果(CATE)治疗效果的突然变化。更具体地说,在每一个时间点,我们考虑一种非对称模式,以允许最大限度的灵活性和稳健性。同时,我们允许对历史共变和噪音功能的时间依赖性。我们提供了一个以内核为基础的改变点估计器,显示在平均时间控制下,其检测延迟程度一致。提供了数字结果,以支持我们的理论发现。