Clinical prediction is an essential task in the healthcare industry. However, the recent success of transformers, on which large language models are built, has not been extended to this domain. In this research, we explore the use of transformers and language models in prognostic prediction for immunotherapy using real-world patients' clinical data and molecular profiles. This paper investigates the potential of transformers to improve clinical prediction compared to conventional machine learning approaches and addresses the challenge of few-shot learning in predicting rare disease areas. The study benchmarks the efficacy of baselines and language models on prognostic prediction across multiple cancer types and investigates the impact of different pretrained language models under few-shot regimes. The results demonstrate significant improvements in accuracy and highlight the potential of NLP in clinical research to improve early detection and intervention for different diseases. Anonymous codes are available at \url{https://anonymous.4open.science/r/table2text-88ED}.
翻译:临床预测是保健行业的一项基本任务,然而,作为大型语言模型基础的变压器最近的成功还没有推广到这一领域。在这个研究中,我们探索使用变压器和语言模型,利用现实世界病人的临床数据和分子剖面进行免疫治疗预测;本文件调查变压器与传统机器学习方法相比,在改进临床预测方面的潜力,并解决在预测罕见疾病地区方面少见学习的挑战。研究为多种癌症类型的预测性预测基准和语言模型的功效提供了基准基准,并在几发制度下调查了不同预先培训的语言模型的影响。研究结果显示,准确性大有提高,并突显了NLP在临床研究中改进早期发现和干预不同疾病的潜力。匿名代码见https://anonymous.4open.science/r/table2text-88ED}。</s>