In spite of its high practical relevance, cluster specific multiple inference for linear mixed model predictors has hardly been addressed so far. While marginal inference for population parameters is well understood, conditional inference for the cluster specific predictors is more intricate. This work introduces a general framework for multiple inference in linear mixed models for cluster specific predictors. Consistent confidence sets for multiple inference are constructed under both, the marginal and the conditional law. Furthermore, it is shown that, remarkably, corresponding multiple marginal confidence sets are also asymptotically valid for conditional inference. Those lend themselves for testing linear hypotheses using standard quantiles without the need of re-sampling techniques. All findings are validated in simulations and illustrated along a study on Covid-19 mortality in US state prisons.
翻译:尽管对线性混合模型预测器具有高度的实际相关性,但迄今尚未讨论对线性混合模型预测器的多组具体推论。虽然对人口参数的边际推论是完全理解的,但对集型特定预测器的有条件推论则更为复杂。这项工作为集群特定预测器的线性混合模型引入了多重推论总框架。在边际法和有条件法下都为多重推论构建了一致的信任体系。此外,还表明,显而易见,对应的多个边际置信体对于有条件推论也同样站不住脚。这些推论可以使用标准的量来测试线性假设物,而不需要再抽样技术。所有结论都经过模拟验证,并随关于美国州监狱Covid-19死亡率的研究进行演示。