Motivated by the problem of measuring the quality of cancer care delivered by providers across the US, we present a framework for institutional quality measurement which addresses the heterogeneity of the public they serve. For this, we conceptualize the task of quality measurement as a causal inference problem, decoupling estimands from estimators, making explicit the assumptions needed for identification, and helping to target flexible covariate profiles that can represent specific populations of interest. We propose methods for layered case-mix adjustments that combine weighting and regression modeling approaches in a sequential manner in order to reduce model extrapolation and allow for provider effect modification. We evaluate these methods in an extensive simulation study and highlight the practical utility of weighting methods that warn the investigator when case-mix adjustments are infeasible without some form of extrapolation that goes beyond the support of the data. Specifically, our constrained optimization approach to weighting constitutes a diagnostic of sparse or null data for a given provider relative to the target profiles. In our study of cancer care outcomes, we assess the performance of oncology practices for different profiles that correspond to different types of patients that may receive cancer care. We describe how the proposed methods may be particularly important for high-stakes quality measurement, such as public reporting or performance-based payments. They may also be important for individual patients seeking practices that provide high-quality care to patients like them. Our approach applies to other settings besides health care, including business and education, where instead of cancer practices, we have companies and schools.
翻译:基于美国各地提供癌症护理者所提供的癌症护理质量的衡量问题,我们提出了一个机构质量计量框架,以解决他们所服务公众的不同性。为此,我们将质量计量任务概念化为因果推断问题,将估计与估计者脱钩,明确确定身份所需的假设,帮助针对能够代表特定受关注人群的灵活共变剖面。我们建议了分层个案调整方法,将加权和回归模型方法相结合,以相继方式减少模型外推法,并允许对提供者的效果进行修改。我们在广泛的模拟研究中评估了这些方法,并强调了当案件混合调整不可行而没有某种超出数据支持范围的外推法时提醒调查员的加权方法的实际效用。具体地说,我们对加权的有限优化方法构成了对某个特定提供者与目标剖面方法相比的稀疏或无效数据的诊断。在癌症护理结果的研究中,我们评估了不同患者不同剖面的肿瘤做法的绩效表现,这些做法与不同类别的病人相对应,包括高质量的病人,在高额的诊断方法上,他们也可能是癌症。