项目名称: 一株自发性出血性脑卒中大鼠的培育
项目编号: No.81473207
项目类型: 面上项目
立项/批准年度: 2015
项目学科: 医药、卫生
项目作者: 苏定冯
作者单位: 中国人民解放军第二军医大学
项目金额: 170万元
中文摘要: 脑卒中具有发病率高、致残率高等特点。目前对脑卒中的发生虽有一些预防措施,但总体效果欠佳。因此,必须深入开展基础研究,找出可干预的靶点为有效地防治脑卒中提供支撑。但是,在实验研究中至今尚缺乏自发性脑出血的动物模型。我们在SP大鼠的基础上培育一株自发性脑出血的动物模型,为发现新的决定或影响脑卒中发生的因素,降低脑卒中的发生率提供基础。
中文关键词: 高血压;脑卒中
英文摘要: Stroke has the feature of high incidence and high morbidity. At present, there are several measures to prevent stroke, but the overall effect is poor. Therefore we must deeply carry out basic research and find out the target for intervention to prevent stroke .However, there is still lack of animal models of spontaneous intracerebral hemorrhage in the experimental study.We develop an animal model of spontaneous cerebral hemorrhage in basal SP rats. It will help to find new factor which is related to incidence of cerebral infarction, and to reduce the incidence of stroke.
英文关键词: hypertension;stroke