Accelerated degradation tests are used to provide accurate estimation of lifetime characteristics of highly reliable products within a relatively short testing time. Data from particular tests at high levels of stress (e.g., temperature, voltage, or vibration) are extrapolated, through a physically meaningful statistical model, to attain estimates of lifetime quantiles at normal use conditions. The gamma process is a natural model for estimating the degradation increments over certain degradation paths, which exhibit a monotone and strictly increasing degradation pattern. In this work, we derive first an algorithm-based optimal design for a repeated measures degradation test with single failure mode that corresponds to a single response component. The univariate degradation process is expressed using a gamma model where a generalized linear model is introduced to facilitate the derivation of an optimal design. Consequently, we extend the univariate model and characterize optimal designs for accelerated degradation tests with bivariate degradation processes. The first bivariate model includes two gamma processes as marginal degradation models. The second bivariate models is expressed by a gamma process along with a mixed effects linear model. We derive optimal designs for minimizing the asymptotic variance for estimating some quantile of the failure time distribution at the normal use conditions. Sensitivity analysis is conducted to study the behavior of the resulting optimal designs under misspecifications of adopted nominal values.
翻译:加速降解试验用于在相对较短的试验时间内准确估计高度可靠产品的寿命特性;通过具有实际意义的统计模型,对高压力水平(例如温度、电压或振动)的特定试验数据进行外推,以得出正常使用条件下的终生孔径估计数;伽马进程是估计某些降解路径的降解增量的自然模型,这些路径显示的是单质的,严格增加的降解模式;在这项工作中,我们首先为反复测量降解试验得出一种基于算法的最佳设计,该测试采用单一失败模式,与单一反应组成部分相对应;在采用通用线性模型来表示单体退化进程;因此,我们扩展了单体孔径模型,并将加速降解试验的最佳设计与双向降解进程相结合;第一个双向模型包括两个伽马进程,作为边际降解模式;第二个双向模型以混合效应线性模型为表示;我们利用伽马进程进行最佳设计,以尽量减少某种具体度差异,以有助于得出最佳设计;因此,在进行正常时间分析时,我们进行了Senariaria的正常分布分析。