Survival models capture the relationship between an accumulating hazard and the occurrence of a singular event stimulated by that accumulation. When the model for the hazard is sufficiently flexible survival models can accommodate a wide range of behaviors. If the hazard model is less flexible, for example when it is constrained by an external physical process, then the resulting survival model can be much too rigid. In this paper I introduce a modified survival model that generalizes the relationship between accumulating hazard and event occurrence with particular emphasis on capturing thresholding behavior. Finally I demonstrate the utility of this approach on a physiological application.
翻译:生存模型可以捕捉累积危险与该累积刺激的单一事件发生之间的关系。 当危险模型足够灵活时, 生存模型可以容纳多种行为。 如果危险模型不太灵活, 例如当它受到外部物理过程的制约时, 由此产生的生存模型可能过于僵硬。 在本文中, 我引入了一个经修改的生存模型, 概括累积危险与事件发生之间的关系, 特别强调捕捉临界行为 。 最后, 我展示了这种方法在生理应用中的实用性 。