In this paper, we present a novel Single-class target-specific Adversarial attack called SingleADV. The goal of SingleADV is to generate a universal perturbation that deceives the target model into confusing a specific category of objects with a target category while ensuring highly relevant and accurate interpretations. The universal perturbation is stochastically and iteratively optimized by minimizing the adversarial loss that is designed to consider both the classifier and interpreter costs in targeted and non-targeted categories. In this optimization framework, ruled by the first- and second-moment estimations, the desired loss surface promotes high confidence and interpretation score of adversarial samples. By avoiding unintended misclassification of samples from other categories, SingleADV enables more effective targeted attacks on interpretable deep learning systems in both white-box and black-box scenarios. To evaluate the effectiveness of SingleADV, we conduct experiments using four different model architectures (ResNet-50, VGG-16, DenseNet-169, and Inception-V3) coupled with three interpretation models (CAM, Grad, and MASK). Through extensive empirical evaluation, we demonstrate that SingleADV effectively deceives the target deep learning models and their associated interpreters under various conditions and settings. Our experimental results show that the performance of SingleADV is effective, with an average fooling ratio of 0.74 and an adversarial confidence level of 0.78 in generating deceptive adversarial samples. Furthermore, we discuss several countermeasures against SingleADV, including a transfer-based learning approach and existing preprocessing defenses.
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