Multilevel modeling is increasingly relevant in the context of modelling and simulation since it leads to several potential benefits, such as software reuse and integration, the split of semantically separated levels into sub-models, the possibility to employ different levels of detail, and the potential for parallel execution. The coupling that inevitably exists between the sub-models, however, implies the need for maintaining consistency between the various components, more so when different simulation paradigms are employed (e.g., sequential vs parallel, discrete vs continuous). In this paper we argue that multilevel modelling is well suited for the simulation of human mobility, since it naturally leads to the decomposition of the model into two layers, the "micro" and "macro" layer, where individual entities (micro) and long-range interactions (macro) are described. In this paper we investigate the challenges of multilevel modeling, and describe some preliminary results using prototype implementations of multilayer simulators in the context of epidemic diffusion and vehicle pollution.
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