While physical activity is critical to human health, most people do not meet recommended guidelines. More walkable built environments have the potential to increase activity across the population. However, previous studies on the built environment and physical activity have led to mixed findings, possibly due to methodological limitations such as small cohorts, few or single locations, over-reliance on self-reported measures, and cross-sectional designs. Here, we address these limitations by leveraging a large U.S. cohort of smartphone users (N=2,112,288) to evaluate within-person longitudinal behavior changes that occurred over 248,266 days of objectively-measured physical activity across 7,447 relocations among 1,609 U.S. cities. By analyzing the results of this natural experiment, which exposed individuals to differing built environments, we find that increases in walkability are associated with significant increases in physical activity after relocation (and vice versa). These changes hold across subpopulations of different genders, age, and body-mass index (BMI), and are sustained over three months after moving.The added activity observed after moving to a more walkable location is predominantly composed of moderate-to-vigorous physical activity (MVPA), which is linked to an array of associated health benefits across the life course. A simulation experiment demonstrates that substantial walkability improvements (i.e., bringing all US locations to the walkability level of Chicago or Philadelphia) may lead to 10.3% or 33 million more Americans meeting aerobic physical activity guidelines. Evidence against residential self-selection confounding is reported. Our findings provide robust evidence supporting the importance of the built environment in directly improving health-enhancing physical activity, in addition to offering potential guidance for public policy activities in this area.
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