Nonignorable missingness and noncompliance can occur even in well-designed randomized experiments making the intervention effect that the experiment was designed to estimate nonidentifiable. Nonparametric causal bounds provide a way to narrow the range of possible values for a nonidentifiable causal effect with minimal assumptions. We derive novel bounds for the causal risk difference for a binary outcome and intervention in randomized experiments with nonignorable missingness caused by a variety of mechanisms and with or without noncompliance. We illustrate the use of the proposed bounds in our motivating data example of peanut consumption on the development of peanut allergies in infants.
翻译:即使在设计得当的随机实验中,也可以出现不可忽略和不遵守现象,这种实验具有干预效果,即试验旨在估算不可识别性。非参数性因果界限提供了一种方法,可以缩小不可识别因果效应的可能值范围,并附有最低限度的假设。我们得出了因果风险差异的新界限,以得出二进制结果,并干预随机试验,不论是否因各种机制而造成不可忽略性缺失。我们举例说明了在我们关于婴儿花生过敏开发的花生消费数据示例中使用拟议界限的情况。