Structural Equation/Causal Models (SEMs/SCMs) are widely used in epidemiology and social sciences to identify and analyze the average causal effect (ACE) and conditional ACE (CACE). Traditional causal effect estimation methods such as Inverse Probability Weighting (IPW) and more recently Regression-With-Residuals (RWR) are widely used - as they avoid the challenging task of identifying the SCM parameters - to estimate ACE and CACE. However, much work remains before traditional estimation methods can be used for counterfactual inference, and for the benefit of Personalized Public Policy Analysis (P$^3$A) in the social sciences. While doctors rely on personalized medicine to tailor treatments to patients in laboratory settings (relatively closed systems), P$^3$A draws inspiration from such tailoring but adapts it for open social systems. In this article, we develop a method for counterfactual inference that we name causal-Graphical Normalizing Flow (c-GNF), facilitating P$^3$A. First, we show how c-GNF captures the underlying SCM without making any assumption about functional forms. Second, we propose a novel dequantization trick to deal with discrete variables, which is a limitation of normalizing flows in general. Third, we demonstrate in experiments that c-GNF performs on-par with IPW and RWR in terms of bias and variance for estimating the ATE, when the true functional forms are known, and better when they are unknown. Fourth and most importantly, we conduct counterfactual inference with c-GNFs, demonstrating promising empirical performance. Because IPW and RWR, like other traditional methods, lack the capability of counterfactual inference, c-GNFs will likely play a major role in tailoring personalized treatment, facilitating P$^3$A, optimizing social interventions - in contrast to the current `one-size-fits-all' approach of existing methods.
翻译:在流行病学和社会科学中广泛使用结构性衡平模型(SEM/SCMS)来估计ACE和CACE。然而,在传统估算方法用于反事实推断以及社会科学中个人化公共政策分析(PQ3A)的惠益之前,仍然有许多工作要做。医生依靠个人化医学来为实验室环境中(相对封闭的系统)的病人提供治疗,P3A则从这种裁缝中得到灵感,但又根据开放的社会系统调整它。在本篇文章中,我们开发了一种相反的推论,比如我们命名了因果-大法标准化流(c-GNF),便利了P3A。首先,我们用个人化公共政策分析(P3P3A)来帮助个人化公共政策分析(P3P3A),同时我们用个个人化医学来为实验室环境中病人提供治疗(相对较高的封闭系统),而P3A则从主要的裁量法中汲取灵感,在公开的社会系统体系中,我们用已知的因果-大变现(RFS-GMA)的演算法,我们用了一个新的变法的演化方法来展示。