The aim of survival analysis in healthcare is to estimate the probability of occurrence of an event, such as a patient's death in an intensive care unit (ICU). Recent developments in deep neural networks (DNNs) for survival analysis show the superiority of these models in comparison with other well-known models in survival analysis applications. Ensuring the reliability and explainability of deep survival models deployed in healthcare is a necessity. Since DNN models often behave like a black box, their predictions might not be easily trusted by clinicians, especially when predictions are contrary to a physician's opinion. A deep survival model that explains and justifies its decision-making process could potentially gain the trust of clinicians. In this research, we propose the reverse survival model (RSM) framework that provides detailed insights into the decision-making process of survival models. For each patient of interest, RSM can extract similar patients from a dataset and rank them based on the most relevant features that deep survival models rely on for their predictions.
翻译:医疗领域生存分析的目的是估计发生某种事件的可能性,例如病人在重症监护单位死亡的概率。最近用于生存分析的深神经网络(DNNs)的发展动态表明这些模型与其他著名的生存分析应用模型相比具有优越性。确保医疗领域部署的深生存模型的可靠性和可解释性是必要的。由于DNN模式的行为通常像黑盒一样,临床医生可能不轻易相信它们的预测,特别是当预测与医生的意见相反时。一个解释和说明其决策过程理由的深度生存模型有可能赢得临床医生的信任。在这个研究中,我们提出了逆向生存模型框架,为生存模型的决策过程提供详细的见解。对于每一个感兴趣的病人,RMM可以从一个数据集中提取类似的病人,并根据深度生存模型预测所依赖的最相关特征排列他们的位置。