A multitude of work has shown that machine learning-based medical diagnosis systems can be biased against certain subgroups of people. This has motivated a growing number of bias mitigation algorithms that aim to address fairness issues in machine learning. However, it is difficult to compare their effectiveness in medical imaging for two reasons. First, there is little consensus on the criteria to assess fairness. Second, existing bias mitigation algorithms are developed under different settings, e.g., datasets, model selection strategies, backbones, and fairness metrics, making a direct comparison and evaluation based on existing results impossible. In this work, we introduce MEDFAIR, a framework to benchmark the fairness of machine learning models for medical imaging. MEDFAIR covers eleven algorithms from various categories, nine datasets from different imaging modalities, and three model selection criteria. Through extensive experiments, we find that the under-studied issue of model selection criterion can have a significant impact on fairness outcomes; while in contrast, state-of-the-art bias mitigation algorithms do not significantly improve fairness outcomes over empirical risk minimization (ERM) in both in-distribution and out-of-distribution settings. We evaluate fairness from various perspectives and make recommendations for different medical application scenarios that require different ethical principles. Our framework provides a reproducible and easy-to-use entry point for the development and evaluation of future bias mitigation algorithms in deep learning. Code is available at https://github.com/ys-zong/MEDFAIR.
翻译:大量工作表明,基于机器的学习医疗诊断系统可能对某些人群群体有偏见,这导致越来越多的旨在解决机器学习中的公平问题的减少偏差算法,目的是解决机器学习中的公平问题;然而,由于两个原因,很难在医疗成像中比较其有效性。第一,对评估公平性的标准缺乏共识。第二,现有的减轻偏差算法是在不同的环境下制定的,例如数据集、示范选择战略、示范选择战略、骨干和公平衡量标准,使得在现有结果不可能的基础上进行直接比较和评价。在这项工作中,我们引入了MEDFAIR,这是衡量机器学习模型对医疗成像的公平性的框架。MEDFAIR涵盖不同类别的11种算法、不同成像模式的9套数据集和3个模式选择标准。通过广泛的实验,我们发现,研究不足的模型选择标准问题可能对公平性结果产生重大影响;相比之下,目前最先进的减轻偏差的减轻偏差算法并没有大大改善在分配和分配外分配环境中的减少经验风险的公平性结果。我们从各种道德观点的角度来评价未来采用各种评价框架,在不同的发展过程中采用。