The real-time analysis of infectious disease surveillance data, e.g., in the form of a time-series of reported cases or fatalities, is essential in obtaining situational awareness about the current dynamics of an adverse health event such as the COVID-19 pandemic. This real-time analysis is complicated by reporting delays that lead to underreporting of the number of events for the most recent time points (e.g., days or weeks). This can lead to misconceptions by the interpreter, e.g., the media or the public, as was the case with the time-series of reported fatalities during the COVID-19 pandemic in Sweden. Nowcasting methods provide real-time estimates of the complete number of events using the incomplete time-series of currently reported events by using information about the reporting delays from the past. Here, we consider nowcasting the number of COVID-19-related fatalities in Sweden. We propose a flexible Bayesian approach, extending existing nowcasting methods by incorporating regression components to accommodate additional information provided by leading indicators such as time-series of the number of reported cases and ICU admissions. By a retrospective evaluation, we show that the inclusion of ICU admissions as a leading signal improved the nowcasting performance of case fatalities for COVID-19 in Sweden compared to existing methods.
翻译:对传染病监测数据的实时分析,例如以报告病例或死亡的时间序列的形式对传染病监测数据进行实时分析,对于了解诸如COVID-19大流行等不良健康事件目前动态的形势至关重要。这种实时分析由于报告延误导致最近时间点(例如几天或几周)的事件数量报告不足而变得复杂。这可能导致翻译(例如媒体或公众)误解,例如媒体或公众误解,如瑞典COVID-19大流行期间报告的死亡人数的时间序列。即时预测方法利用关于过去报告延误的信息,对目前报告的事件的不完整时间序列提供对事件全数的实时估计。我们在这里考虑现在预测与COVID-19有关的事件数量。我们提议一种灵活的巴伊西亚办法,通过纳入回归部分来扩大现有的播报方法,以适应所报告的案件数量和ICU的承认程度等主要指标提供的额外信息。我们通过回顾性评估,现在显示,在将COVI-19大事件的现有死亡率分析方法纳入现有的COU入院后,我们比证了瑞典的死亡率。