Data-driven decision making plays an important role even in high stakes settings like medicine and public policy. Learning optimal policies from observed data requires a careful formulation of the utility function whose expected value is maximized across a population. Although researchers typically use utilities that depend on observed outcomes alone, in many settings the decision maker's utility function is more properly characterized by the joint set of potential outcomes under all actions. For example, the Hippocratic principle to ``do no harm'' implies that the cost of causing death to a patient who would otherwise survive without treatment is greater than the cost of forgoing life-saving treatment. We consider optimal policy learning with asymmetric utility functions of this form. We show that asymmetric utilities lead to an unidentifiable social welfare function, and so we first partially identify it. Drawing on statistical decision theory, we then derive minimax decision rules by minimizing the maximum regret relative to alternative policies. We show that one can learn minimax decision rules from observed data by solving intermediate classification problems. We also establish that the finite sample regret of this procedure is bounded by the mis-classification rate of these intermediate classifiers. We apply this conceptual framework and methodology to the decision about whether or not to use right heart catheterization for patients with possible pulmonary hypertension.
翻译:即便在医学和公共政策等高风险环境中,数据驱动的决策也起着重要作用。从观察到的数据中学习最佳政策要求谨慎地制定其预期价值在人口中最大化的公用功能。虽然研究人员通常使用仅依赖于观察到的结果的公用设施,但在许多环境中,决策者的公用功能更恰当地以所有行动下的潜在结果组合为特征。例如,Hippocrip 原则“不造成伤害”意味着,在没有治疗本可以生存而得不到治疗的病人死亡的代价大于持续救生治疗的费用。我们考虑以这种形式的不对称公用功能进行最佳政策学习。我们表明,不对称公用设施导致一种无法识别的社会福利功能,因此我们首先部分地确定这种功能。根据统计决策理论,我们然后通过最大限度地减少相对于替代政策的最大遗憾来得出微小决定规则。我们表明,通过解决中间分类问题,可以从所观察到的数据中小决定来学习小决定规则。我们还确定这一程序的有限抽样遗憾受这些中间分类师错误分类率的约束。我们将这些概念框架和方法应用于心脏高血压决定是否使用正确。