Predicting the future development of an anatomical shape from a single baseline is an important but difficult problem to solve. Research has shown that it should be tackled in curved shape spaces, as (e.g., disease-related) shape changes frequently expose nonlinear characteristics. We thus propose a novel prediction method that encodes the whole shape in a Riemannian shape space. It then learns a simple prediction technique that is founded on statistical hierarchical modelling of longitudinal training data. It is fully automatic, which makes it stand out in contrast to parameter-rich state-of-the-art methods. When applied to predict the future development of the shape of right hippocampi under Alzheimer's disease, it outperforms deep learning supported variants and achieves results on par with state-of-the-art.
翻译:从单一基线预测解剖形状的未来发展是一个重要但困难的问题,需要解决。研究显示,应该用曲线形状空间来解决这个问题,因为(例如,与疾病有关的)形状变化经常暴露非线性特征。因此,我们提出了一个新颖的预测方法,将整个形状编码于里曼尼形空间,然后学习一种简单的预测技术,以纵向培训数据的统计等级建模为基础。这是完全自动的,它与富于参数的先进方法形成鲜明对比。当应用来预测阿尔茨海默氏病下右河马坎皮形状的未来发展时,它优于深层学习所支持的变体,并取得与最新技术相同的结果。