Recently, the coronavirus disease 2019 (COVID-19) has caused a pandemic disease in over 200 countries, influencing billions of humans. To control the infection, identifying and separating the infected people is the most crucial step. The main diagnostic tool is the Reverse Transcription Polymerase Chain Reaction (RT-PCR) test. Still, the sensitivity of the RT-PCR test is not high enough to effectively prevent the pandemic. The chest CT scan test provides a valuable complementary tool to the RT-PCR test, and it can identify the patients in the early-stage with high sensitivity. However, the chest CT scan test is usually time-consuming, requiring about 21.5 minutes per case. This paper develops a novel Joint Classification and Segmentation (JCS) system to perform real-time and explainable COVID-19 chest CT diagnosis. To train our JCS system, we construct a large scale COVID-19 Classification and Segmentation (COVID-CS) dataset, with 144,167 chest CT images of 400 COVID-19 patients and 350 uninfected cases. 3,855 chest CT images of 200 patients are annotated with fine-grained pixel-level labels of opacifications, which are increased attenuation of the lung parenchyma. We also have annotated lesion counts, opacification areas, and locations and thus benefit various diagnosis aspects. Extensive experiments demonstrate that the proposed JCS diagnosis system is very efficient for COVID-19 classification and segmentation. It obtains an average sensitivity of 95.0% and a specificity of 93.0% on the classification test set, and 78.5% Dice score on the segmentation test set of our COVID-CS dataset. The COVID-CS dataset and code are available at https://github.com/yuhuan-wu/JCS.
翻译:最近,2019年的冠状病毒疾病(COVID-19)在200多个国家造成了流行病,影响到数十亿人类。但是,为了控制感染,确定和隔离受感染者,这是最重要的一步。主要诊断工具是逆转Trancation 聚合酶链反应(RT-PCR)测试。不过,RT-PCR测试的敏感性不足以有效预防这一流行病。胸部CT扫描测试为RT-PCR测试提供了宝贵的补充工具。它能够以高度敏感度识别早期的病人。然而,胸部CT扫描测试通常耗时,每起案件需要约21.5分钟的时间。主要诊断工具是逆转 Transmation Transmation 聚合酶链反应(RT-PCR)测试。尽管如此,RT-PCR的敏感度不足以有效预防这一流行病。我们建造了大规模COVID-19分类和分解(COVID-CR)数据库,有144,167个胸前CT分类图像是400 DVI-19病人和350个未受感染的病例。 该文件开发了一个新的联合分类和分解点的CSD-CF 数据系统。3,855的值测试区域,因此,用于CSD-CSD-CSD-dealation的值的值值值值值值数据区域。