Using histopathological images to automatically classify cancer is a difficult task for accurately detecting cancer, especially to identify metastatic cancer in small image patches obtained from larger digital pathology scans. Computer diagnosis technology has attracted wide attention from researchers. In this paper, we propose a noval method which combines the deep learning algorithm in image classification, the DenseNet169 framework and Rectified Adam optimization algorithm. The connectivity pattern of DenseNet is direct connections from any layer to all consecutive layers, which can effectively improve the information flow between different layers. With the fact that RAdam is not easy to fall into a local optimal solution, and it can converge quickly in model training. The experimental results shows that our model achieves superior performance over the other classical convolutional neural networks approaches, such as Vgg19, Resnet34, Resnet50. In particular, the Auc-Roc score of our DenseNet169 model is 1.77% higher than Vgg19 model, and the Accuracy score is 1.50% higher. Moreover, we also study the relationship between loss value and batches processed during the training stage and validation stage, and obtain some important and interesting findings.
翻译:使用病理学图像对癌症进行自动分类是准确检测癌症的一项困难任务,特别是要查明从大型数字病理学扫描中获得的小图像片段中的转移性癌症。 计算机诊断技术吸引了研究人员的广泛关注。 在本文中,我们提出了将图像分类、 DenseNet169 框架和 Recited Adam 优化算法等深层次学习算法相结合的无比方法。 DenseNet 的连接模式是从任何层到所有连续层的直接连接,这可以有效地改善不同层之间的信息流动。 由于RADam不易落入一个地方最佳解决方案,而且可以在模型培训中迅速融合。 实验结果显示,我们的模型取得了优于其他古典的神经神经网络方法, 如Vgg19、Resnet34、Resnet50。 特别是,我们的DenseNet169 模型的Auc-Roc得分比比Vgg19 模型高出1.77%, 而Accurity的得分则高出1.5 %。 此外,我们还研究了在培训阶段和验证阶段处理的损失价值与分数之间的关系, 并取得了一些重要和令人感兴趣的结果。