The screening testing is an effective tool to control the early spread of an infectious disease such as COVID-19. When the total testing capacity is limited, we aim to optimally allocate testing resources among n counties. We build a (weighted) commute network on counties, with the weight between two counties a decreasing function of their traffic distance. We introduce a network-based disease model, in which the number of newly confirmed cases of each county depends on the numbers of hidden cases of all counties on the network. Our proposed testing allocation strategy first uses historical data to learn model parameters and then decides the testing rates for all counties by solving an optimization problem. We apply the method on the commute networks of Massachusetts, USA and Hubei, China and observe its advantages over testing allocation strategies that ignore the network structure. Our approach can also be extended to study the vaccine allocation problem.
翻译:筛查是控制传染病(如COVID-19)早期传播的有效工具。当总体检测能力有限时,我们的目标是在各州之间优化分配检测资源。我们在各州之间建立一个(加权)通勤网络,两个州之间的重量因交通距离而下降。我们引入了基于网络的疾病模式,其中每个州新确认的病例数量取决于网络中所有县的隐藏病例数量。我们提议的测试分配战略首先利用历史数据学习模型参数,然后通过解决优化问题决定所有县的测试率。我们在麻省、美国和中国湖北的通勤网络上应用这种方法,并观察其在无视网络结构的测试分配战略方面的优势。我们的方法还可以扩大到研究疫苗分配问题。