Colorectal cancer (CRC) is the third most frequent malignant disease in the world. In some countries with established screening programs, its incidence and mortality have decreased, and survival has improved. AIMS: To obtain reliable data about the epidemiology of CRC in Chile, we analyzed the trends in the last ten years and the influence of observable factors on survival, including explicit guarantees in CRC treatment access (GES program). Publicly available data published by the Health Ministry and National Institute of Statistics were used. Data were obtained from registries of mortality and hospital discharges, making follow-up of the individuals possible. Crude and age-standardized incidence and mortality rates were calculated, and individual survival was studied by constructing Kaplan-Meier curves. Finally, a Cox statistical model was established to estimate the impact of the observable factors.
翻译:直肠癌(CRC)是世界上第三大常见恶性疾病,在一些已制定检查方案的国家,其发病率和死亡率有所下降,存活率也有所改善。AIMS:为了获得有关智利CRC流行病学的可靠数据,我们分析了过去十年的趋势和可观测因素对生存的影响,包括《儿童权利公约》治疗的明确保障(GES方案),卫生部和国家统计研究所公布的公开数据得到了使用。数据来自死亡率和医院出院登记簿,从而有可能对患者采取后续行动。计算出粗略和年龄标准化的发病率和死亡率,并通过建造卡普兰-梅耶曲线对个人存活率进行了研究。最后,建立了Cox统计模型,以估计可观测因素的影响。