In this paper, we address the inference problem in high-dimensional linear expectile regression. We transform the expectile loss into a weighted-least-squares form and apply a de-biased strategy to establish Wald-type tests for multiple constraints within a regularized framework. Simultaneously, we construct an estimator for the pseudo-inverse of the generalized Hessian matrix in high dimension with general amenable regularizers including Lasso and SCAD, and demonstrate its consistency through a new proof technique. We conduct simulation studies and real data applications to demonstrate the efficacy of our proposed test statistic in both homoscedastic and heteroscedastic scenarios.
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