Cu基金属纳米晶：结构调控和催化Ullmann反应研究

项目名称： Cu基金属纳米晶：结构调控和催化Ullmann反应研究

项目编号： No.21471089

项目类型： 面上项目

立项/批准年度： 2015

项目学科： 无机化学

项目作者： 王定胜

作者单位： 清华大学

项目金额： 80万元

中文摘要： Ullmann反应作为构建芳香碳-碳和碳-杂键的重要途径，一直是有机合成的研究热点之一。发展新型高效催化剂对于改进Ullmann反应具有重要的科学意义和工业应用价值。Cu基金属纳米晶催化剂相对于传统的Cu基金属配合物催化剂具有无配体、易回收、催化活性及选择性易于调控等优势。本项目拟：（1）发展Cu基金属纳米晶的合成方法，实现系列Cu基双金属及多金属纳米晶的可控制备；（2）实现Cu基金属纳米晶的结构调控，探索纳米晶催化剂结构对于催化Ullmann反应性能的影响，从而实现对Ullmann反应催化活性和选择性的调控；（3）在认识纳米晶催化剂作用机理的基础上发现新的Ullmann反应。本项目对于开发新型Cu基金属纳米晶催化剂、深入研究Cu催化Ullmann反应机理、扩展Ullmann反应类型及推动Ullmann反应的工业化应用具有重要意义。

中文关键词： Cu；纳米晶；结构调控；Ullmann反应

英文摘要： Ullmann reaction, as an important way to build aromatic carbon-carbon and carbon-hybrid bond, has been a hot area of research in organic synthesis. It has important scientific significance and industrial applications to develop new efficient catalysts for improving the Ullmann reaction. Compared to traditional Cu-based metal complex catalysts, Cu-based metal nanocrystal catalysts have some advantages including free of complexes, easy recovery, and easy control on catalytic activity and selectivity. This project focuses on: (1) developing synthetic methods for Cu-based metal nanocrystals and achieving controllable preparation of a series of Cu-based bimetallic and multi-metallic nanocrystals; (2) achieving structural control for Cu-based metal nanocrystals, investigating the influence of microstructure of nanocrystal catalysts on their catalytic performance for Ullmann reaction, and achieving control on catalytic activity and selectivity; (3) discovering new Ullmann reaction based on understanding the mechanism of nanocrystalline catalysts. This project helps to exploit novel Cu-based metal nanocrystal catalysts for Ullmann reaction and reveal the mechanism of nanocrystalline catalysts, and has scientific significance and practical value in developing Ullmann reaction and promoting its industrial applications.

英文关键词： Cu;nanocrystals;structural control;Ullmann reaction