人工耳蜗丰富音感知处理策略与光诱发听觉若干问题研究

项目名称： 人工耳蜗丰富音感知处理策略与光诱发听觉若干问题研究

项目编号： No.11474185

项目类型： 面上项目

立项/批准年度： 2015

项目学科： 数理科学和化学

项目作者： 田岚

作者单位： 山东大学

项目金额： 85万元

中文摘要： 研究证实,现有人工耳蜗（CI）对音乐等丰富音感知仍不佳，其中频谱成分及信号时序丢失或或错位是金属电极式CI不易跨越的障碍。近几年，国外首先发起激光诱发听觉研究，开辟了CI发展新方向。与金属电极相比，光纤激光无源，芯细，方向性好，可密集分布且信号互不干扰，刺激模式限制少，在精确传导丰富音频谱和时序信号阵列上更具优势和潜力。本项目首先基于信号处理理论和光电转换技术建立人工光学仿生耳研究平台，研究声音阵列信号时序和光信号转换方法，通过嵌合声实验，掌握音效感知与声谱成分及信号时序的对应关系，进而提出信号编码的改进处理策略和光诱发听觉新方案。 在光诱发听觉研究中，首先以动物听觉系统为观测对象，采用神经电生理测量和显微成像技术，搞清光刺激信号与听神经信号发放的关系，测定激光安全、有效诱发听觉的各项参数，如波长、功率、调制方式、光纤最小间隔等，以构建基于光纤阵列刺激策略的新型人工耳蜗系统。

中文关键词： 耳蜗植入；处理策略；听觉感知；激光技术；光纤

英文摘要： Among the existing electrical cochlear implant products, musical signal perception performance is still poor. The loss or mismatch of detailed frequency structure and signal timing is a limitation to metal electrode type CI. To explore the improvement of cochlear implants' performance, foreign scientists began trying to use laser pulse as s stimulus to evoke neural activity. Compared with the metal electrodes, optical fiber with thinner core is passive and the laser has good directivity. The fibers have intensive distribution without signal interference and limitation of stimulation patterns, whichhas more advantages and potentialin precise acoustic spectrum and temporal signal array transmissions. This project, in the first step, establishes artificial optical bionic ears research platform based on the theory of signal processing and photo-electric conversion technology. Research on the time sequence of voice array signal and optical signalconversion method will be implemented. With the help of chimeric acoustic experiment,the relationship between musical perception,acoustic spectrum composition and signal timing will be studied. New method of improving the signal coding strategy and light evoked auditory response will be put forward. In the research of light evoked auditory response,we take the animal auditory system as the observation object.With the neural electrophysiological measurement and microscopic imaging technology, the relationship betweenlight stimulus signal and auditory nervesignal will be discussed. The effective and safe parameters of laser, such as wavelength, energy, modulation mode, optical fiber's minimum interval will be measured to build a new type of cochlear implantsystem based on optical fiber array stimulation strategy .

英文关键词： cochlear implant;processing strategy;auditory perception;laser technology;optical fiber