植物体中多溴联苯醚及其羟基与甲氧基衍生物的转化特征与机制研究

项目名称： 植物体中多溴联苯醚及其羟基与甲氧基衍生物的转化特征与机制研究

项目编号： No.41303073

项目类型： 青年科学基金项目

立项/批准年度： 2014

项目学科： 天文学、地球科学

项目作者： 王森

作者单位： 西北大学

项目金额： 25万元

中文摘要： 多溴联苯醚（PBDEs）是一类重要的新型持久性有机污染物，易在环境中累积，会发生还原和氧化代谢生成毒性更大的低溴代、羟基和甲氧基衍生物。但是目前关于陆生生态系统中PBDEs及其衍生物转化行为的认识非常有限。本项目重点研究植物体中PBDEs及其羟基和甲氧基衍生物的转化特征与机制。通过野外采样与分析，揭示PBDEs及其羟基和甲氧基衍生物在典型电子垃圾拆解地植物中的分布规律；应用14C同位素技术探讨植物体内羟基和甲氧衍生物的来源；通过实验室暴露实验，阐明植物体中PBDEs及其羟基和甲氧基衍生物之间的转化特征；应用分子生物学手段揭示植物体内PBDEs及其羟基和甲氧基衍生物转化的生物机制。本研究核心目的是明确植物体中PBDEs及其羟基与甲氧基衍生物的转化特征与机制，加深对陆生生态系统中PBDEs及其衍生物环境行为的认识，为其生态和健康风险评价提供科学依据。

中文关键词： 植物；多溴联苯醚；羟基多溴联苯醚；甲氧基多溴联苯醚；分子机制

英文摘要： Polybrominated diphenyl ethers (PBDEs) are emerging new persistent organic pollutants (POPs) that are liable to accumulate in the environmental matrices. Moreover, PBDEs in the environment can degrade to other brominated derivatives through the debrominated reductive metabolism and the oxidative metabolism of hydroxylation and methoxylation. However, so far very few studies have dealt with transformation of PBDEs and their derivatives in terrestrial ecosystems. The aim of this research project is to investigate the transformation characteristic and mechanisms of PBDEs and their hydroxylated, methoxylated derivatives (OH-PBDEs and MeO-PBDEs) in plants. Research details include: 1) investigate occurrence and distribution of PBDEs, OH-PBDEs and MeO-PBDEs in plants from the e-waste area; 2) educidate the translocation and transformation characteristic of PBDEs, OH-PBDEs and MeO-PBDEs in plants through hydroponic experiment in laboratory; 3) use molecular-level radiocarbon analysis to discuss the origin of OH-PBDEs and MeO-PBDEs in plants; 4) use molecular biotechnology to elucidate the transformation mechanisms of PBDEs, OH-PBDEs and MeO-PBDEs in plants. The research of this proposal is of significance in elucidating the transformation characteristic and mechanisms of PBDEs and their hydroxylated, methoxylated deriv

英文关键词： Plant；PBDEs；OH-PBDEs；MeO-PBDEs；Molecular mechanisms