Many economic panel and dynamic models, such as rational behavior and Euler equations, imply that the parameters of interest are identified by conditional moment restrictions with high dimensional conditioning instruments. We develop a novel inference method for the parameters identified by conditional moment restrictions, where the dimension of the conditioning instruments is high and there is no prior information about which conditioning instruments are weak or irrelevant. Building on Bierens (1990), we propose penalized maximum statistics and combine bootstrap inference with model selection. Our method optimizes the asymptotic power against a set of $n^{-1/2}$-local alternatives of interest by solving a data-dependent max-min problem for tuning parameter selection. We demonstrate the efficacy of our method by two empirical examples: the elasticity of intertemporal substitution and rational unbiased reporting of ability status. Extensive Monte Carlo experiments based on the first empirical example show that our inference procedure is superior to those available in the literature in realistic settings.
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