As the coronavirus disease 2019 (COVID-19) has shown profound effects on public health and the economy worldwide, it becomes crucial to assess the impact on the virus transmission and develop effective strategies to address the challenge. A new statistical model derived from the SIR epidemic model with functional parameters is proposed to understand the impact of weather and government interventions on the virus spread in the presence of asymptomatic infections among eight metropolitan areas in the United States. The model uses Bayesian inference with Gaussian process priors to study the functional parameters nonparametrically, and sensitivity analysis is adopted to investigate the main and interaction effects of these factors. This analysis reveals several important results including the potential interaction effects between weather and government interventions, which shed new light on the effective strategies for policymakers to mitigate the COVID-19 outbreak.
翻译:由于2019年冠状病毒疾病(COVID-19)对全世界公共卫生和经济的深刻影响,评估病毒传播的影响并制定有效战略来应对这一挑战变得至关重要,根据SIR流行病模式提出的具有功能参数的新统计模型旨在了解天气和政府干预对在美国八个大都市地区无症状感染的情况下传播病毒的影响。模型在研究功能参数之前先使用巴耶斯与高斯进程的推断,采用敏感性分析,以调查这些因素的主要和相互作用影响。这一分析揭示了若干重要结果,包括天气和政府干预之间的潜在互动影响,为决策者减轻COVID-19爆发的有效战略提供了新的启示。