In observational studies, when a total causal effect of interest is not identified, the set of all possible effects can be reported instead. This typically occurs when the underlying causal DAG is only known up to a Markov equivalence class, or a refinement thereof due to background knowledge. As such, the class of possible causal DAGs is represented by a maximally oriented partially directed acyclic graph (MPDAG), which contains both directed and undirected edges. We characterize the minimal additional edge orientations required to identify a given total effect. A recursive algorithm is then developed to enumerate subclasses of DAGs, such that the total effect in each subclass is identified as a distinct functional of the observed distribution. This resolves an issue with existing methods, which often report possible total effects with duplicates, namely those that are numerically distinct due to sampling variability but are in fact causally identical.
翻译:在观察研究中,当没有查明利益的全部因果关系时,可以报告所有可能的效应,这通常发生在根因DAG只在Markov等效等级之前才知道,或由于背景知识而对其加以改进时。因此,可能的因果DAG的类别由一个方向最大化、部分定向的环流图(MPDAG)代表,该图既包含定向边缘,也包含非定向边缘。我们描述为确定特定总效果所需的最低限度的额外边缘方向。然后,开发一种循环算法,以罗列DAG的子类,这样,每个子类的总效果被确定为所观察到分布的不同功能。这解决了与现有方法有关的问题,这些方法往往报告可能的总效果与重复,即由于抽样差异而具有数字上区别但事实上在因果关系上完全相同的那些方法。