This work is concerned with epidemiological models defined on networks, which highlight the prominent role of the social contact network of a given population in the spread of infectious diseases. In particular, we address the modelling and analysis of very large networks. As a basic epidemiological model, we focus on a SEIR (Susceptible-Exposed-Infective-Removed) model governing the behaviour of infectious disease among a population of individuals, which is partitioned into sub-populations. We study the long-time behaviour of the dynamic for this model that considers the heterogeneity of the infections and the social network. By relying on the theory of graphons we explore the natural question of the large population limit and investigate the behaviour of the model as the size of the network tends to infinity. After establishing the existence and uniqueness of solutions to the models that we will consider, we discuss the possibility of using the graphon-based limit model as a generative model for a network with particular statistical properties relating to the distribution of connections. We also provide some preliminary numerical tests.
翻译:这项工作涉及在网络上界定的流行病学模式,这些模式突出了特定人群的社会联系网络在传染病传播中的突出作用,特别是,我们处理非常庞大网络的建模和分析。作为一个基本的流行病学模式,我们侧重于指导个人群体传染病行为的SEI(可视-可施用-感染-可移植)模式,该模式被分为亚人口。我们研究了这一模式的动态的长期行为,该模式考虑了感染和社会网络的异质性。我们利用图表理论来探讨人口大限的自然问题,并调查模型的行为,因为网络的规模往往不尽相同。在确定了我们将要考虑的模型的解决办法的存在和独特性之后,我们讨论了使用基于图表的限制模式作为具有与连接分布有关的特定统计特性的网络的基因化模型的可能性。我们还提供一些初步的数字测试。